Lilly is among the top 10 global pharmaceutical companies. Since its establishment, more than 135 years ago, the company has been committed to the discovery, development and marketing of innovative medicines worldwide. Currently, it has the pipeline with the highest number of molecules in the final stages of development since it was established. Lilly is among the top 5 companies within several crucial therapeutic areas for public health, including diabetes, oncology, neuroscience and veterinary. The Italian subsidiary's activity began about 50 years ago, the Italian office is located in Sesto Fiorentino (Florence). Currently, Lilly Italia achieved constant growth in its scientific, manufacturing and financial results, with a turnover in 2012 of 634 million Euros. The largest plant was built in Sesto Fiorentino for the production of biotechnology medicine in Italy, intended for the production of recombinant DNA insulin for European and non-European countries.